Contact information
BIOGRAPHY
Kanmin Xue, MB BChir PhD FRCOphth, is a Wellcome Trust clinician scientist fellow at the University of Oxford and Honorary Consultant Vitreoretinal Surgeon at the Oxford Eye Hospital. He previously held the role of National Institute for Health Research (NIHR) Academic Clinical Lecturer in Oxford between 2014 and 2018, conducting laboratory and clinical research into gene therapy for inherited retinal diseases, robotic eye surgery and artificial retinal implant with Professor Robert MacLaren. He has completed the UK specialist training in ophthalmology and a vitreoretinal fellowship at the Royal Victorian Eye and Ear Hospital in Melbourne, Australia. He previously conducted PhD research at the MRC Laboratory of Molecular Biology in Cambridge into how DNA editing brings about antibody class switching, underwent clinical training at Trinity College Cambridge, and pre-clinical training at Brasenose College Oxford, where he was awarded Martin Wronker Prize for the top First Class in Medicine.
AWARDS
Ruskell Medal 2019
Ian Fraser Cup 2017
Luigi Barca Award 2017
Martin Wronker Prize in Medicine 2003
Kanmin Xue
MA MB BChir PhD FRCOphth
Wellcome Trust Clinical Research Career Development Fellow
- Honorary Consultant Ophthalmologist, Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust
Research
Kanmin leads the Retinal Disease and Repair Group investigating the mechanisms of retinal inflammation, degeneration and novel genetic therapies for retinal diseases. In association with Professor Robert MacLaren, he led the retinal gene therapy clinical trials for choroideremia and X-linked retinitis pigmentosa in Oxford and the world's first clinical trial of robot-assisted retinal surgery.
Team members
Joel Quinn, Research Assistant
Laurel Chandler, DPhil candidate (Merton College Oxford)
Thomas Willis Poster Prize 2019
Oxford-Bristol-Cardiff-Southampton Alliance in Vision Research Best Poster Prize 2017
Past students
Ayesha Musa, FHS student 2020 (Jesus College Oxford)
James Aylward, BM-BCh (St Hilda's College Oxford)
Dun Jack Fu, BM-BCh PhD (St Hugh's College Oxford)
Olivia Parham, FHS student 2016 (New College Oxford)
Howell Fu, FHS student 2015 (Exeter College Oxford)
Key publications
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Journal article
Quinn J. et al, (2020), Hum Gene Ther
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Journal article
Xue K. and MacLaren RE., (2020), Expert Opin Investig Drugs, 29, 1163 - 1170
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Journal article
Chandler LC. et al, (2019), Mol Ther Methods Clin Dev, 14, 77 - 89
Recent publications
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Journal article
Cehajic Kapetanovic J. et al, (2020), Acta Ophthalmol, 98, 736 - 740
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Journal article
Cehajic-Kapetanovic J. et al, (2020), Acta Ophthalmol
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Journal article
Xue K. and MacLaren RE., (2020), Expert Opin Investig Drugs, 29, 1163 - 1170
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Journal article
Quinn J. et al, (2020), Hum Gene Ther
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Journal article
Xue K. and MacLaren RE., (2020), Curr Opin Physiol, 16, 1 - 7
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Journal article
Chandler LC. et al, (2020), Int J Mol Sci, 21
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Cell-Mediated Inflammatory Response to AAV Gene Therapy in the Retina
Conference paper
Chandler LC. et al, (2020), MOLECULAR THERAPY, 28, 515 - 516
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Looking towards gene therapy: Characterisation of ex vivo AAV2.CYP4V2 gene therapy in human retinal explants
Conference paper
Hu M. et al, (2019), CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 47, 113 - 113
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Journal article
Chandler LC. et al, (2019), Mol Ther Methods Clin Dev, 14, 77 - 89
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Photoreceptor atrophy independent of retinal hemorrhages in Terson syndrome
Conference paper
Xue K. et al, (2019), INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 60