Research groups
Websites
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Wellcome Centre for Integrative Neuroimaging
Centre
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Nuffield Department of Clinical Neurosciences
Department
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Oxford Sparks
My 'meet the scientist' profile
Stuart Clare
PhD
Associate Professor and Director of Operations, WIN
The last twenty years have seen a huge leap forward in our understanding of how the human brain works, and forefront in the technologies that have enabled this is the technique of functional Magnetic Resonance Imaging (fMRI). My research program involves pushing the technological boundaries of the MRI technique to reveal new insights about how the brain functions normally, and how it is affected by disease.
In 2011 the FMRIB Centre installed a state-of-the-art MRI scanner operating at a magnetic field strength of 7 Tesla. This is over 5 times stronger than a standard clinical system and enables the structure and function of the brain to be studied in far higher detail than has previously been possible.
As well as facilitating clinical and neuroscience research on the Centre's MRI scanners, and leading the Centre's core team, I have a research interest in improving the quality of MRI images using a technique called 'dynamic shimming'.
I am heavily involved in communicating the research we do to the general public (for example, see the animation on the left) and have been working with schools to inspire the next generation of scientists.
Key publications
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Shim optimization with region of interest-specific Tikhonov regularization: Application to second-order slice-wise shimming of the brain.
Journal article
Shi Y. et al, (2021), Magn Reson Med
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Template-based field map prediction for rapid whole brain B0 shimming.
Journal article
Shi Y. et al, (2018), Magn Reson Med, 80, 171 - 180
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Multi-Site Harmonization of 7 Tesla MRI Neuroimaging Protocols
Journal article
CLARKE W. et al, (2019), NeuroImage
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Feasibility of Diffusion Tensor and Morphologic Imaging of Peripheral Nerves at Ultra-High Field Strength.
Journal article
Schmid AB. et al, (2018), Invest Radiol, 53, 705 - 713
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Delineating extrastriate visual area MT(V5) using cortical myeloarchitecture.
Journal article
Bridge H. et al, (2014), Neuroimage, 93 Pt 2, 231 - 236
Recent publications
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Quantitative susceptibility mapping at 7 T in COVID-19: brainstem effects and outcome associations.
Journal article
Rua C. et al, (2024), Brain
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Shim optimization with region of interest-specific Tikhonov regularization: Application to second-order slice-wise shimming of the brain.
Journal article
Shi Y. et al, (2021), Magn Reson Med
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Multi-centre, multi-vendor reproducibility of 7T QSM and R2* in the human brain: Results from the UK7T study.
Journal article
Rua C. et al, (2020), Neuroimage, 223
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European Ultrahigh-Field Imaging Network for Neurodegenerative Diseases (EUFIND).
Journal article
Düzel E. et al, (2019), Alzheimers Dement (Amst), 11, 538 - 549
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Multi-Site Harmonization of 7 Tesla MRI Neuroimaging Protocols
Journal article
CLARKE W. et al, (2019), NeuroImage