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Rupert McShane


Dementia Clinical Network Lead - Oxford Academic Health Science Network

  • Consultant Psychiatrist

I am interested in treatment resistant depression and dementia.  Clinically, I lead the Oxfordshire ECT and ketamine service, and run a memory clinic

Following an NIHR-funded case series exploring the use of repeated ketamine for resistant depression, we have now treated over 100 patients and are continuing to refine treatment protocols.  I led a qualitative study of ECT, which led to the creation of a Healthtalk module of patients talking about their experience and an exploration of why experiences are so polarised.

I support research as local PI for commercial and NIHR funded dementia trials and of esketamine for treatment resistant depression. 

As Coordinating Editor of the Cochrane Dementia and Cognitive Improvement Group I have led programmes on reviews of diagnostic test accuracy, and modifiable risk factors in dementia.  I lead the Clinical Dementia Network of the Oxford Academic Health Science Network, which covers Thames Valley. I am currently exploring the use of telematics to help older people decide if they are still safe to drive. 

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Recent Publications

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