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- Neuromuscular Disorders Research Group
Senior Post-doctoral Research Scientist
I joined the research group of Prof Beeson in 2000 after the completion of my PhD from the University of London. I’m interested in the functional analysis of neuromuscular transmission from the whole animal to the single channel. I am a senior electrophysiologist with expertise in many aspects of measuring neurotransmission. Our goal is to understand the molecular mechanisms that enable neuromuscular transmission and to determine what underlies the pathophysiology seen in patients with Congenital Myasthenic Syndromes.
Characterization of an anti-fetal AChR monoclonal antibody isolated from a myasthenia gravis patient.
Saxena A. et al, (2017), Sci Rep, 7
Multiple roles of integrin-α3 at the neuromuscular junction.
Ross JA. et al, (2017), J Cell Sci, 130, 1772 - 1784
Fast-channel congenital myasthenic syndrome with a novel acetylcholine receptor mutation at the α-ε subunit interface
Webster R. et al, (2014), Neuromuscular Disorders, 24, 143 - 147
A mouse model of the slow channel myasthenic syndrome: Neuromuscular physiology and effects of ephedrine treatment.
Webster RG. et al, (2013), Exp Neurol, 248, 286 - 298
Mutations in GFPT1 that underlie limb-girdle congenital myasthenic syndrome result in reduced cell-surface expression of muscle AChR.
Zoltowska K. et al, (2013), Hum Mol Genet, 22, 2905 - 2913