Ludovica Griffanti
Contact information
Colleges
Ludovica Griffanti
PhD
Associate Professor
- NIHR Oxford Senior Research Fellow
Research Summary
I am a researcher at the Wellcome Centre for Integrative Neuroimaging (WIN), passionate about making research translational and applicable in clinical settings.
In my group we develop image analysis tools for clinical applications. Our main projects are part of the NIHR Oxford Health Biomedical Research Centre (OH-BRC). Under the dementia theme, we aim to translate research knowledge and quantitative measurements from brain MRI in memory clinic through the Oxford Brain Health Clinic. Under the brain technologies theme we aim to harmonise MRI-derived measures across studies and sites, to be able to compare scans across groups or a single scans to a reference distribution, regardless of where they were acquired.
As a member of the WIN Analysis group I am also involved in the development of methodological approaches for structural MRI (automated lesions segmentation) and resting state fMRI (artefact removal and reproducibility assessments) part of the FSL image analysis software package.
I completed my undergraduate studies and a PhD in Bioengineering at Politecnico di Milano (Milan, Italy) before moving to University of Oxford as a postdoctoral researcher and then Alzheimer's Association Research Fellow. I have worked on and collaborate on studies on brain imaging analysis in ageing, Alzheimer’s disease, Parkinson’s disease and vascular disease.
Teaching and Training
I am involved in post-graduate supervision and in teaching, both within the University of Oxford and externally.
- MSc in clinical and therapeutic neuroscience (Oxford) - lecturer on the MRI analysis module
- MSc in Experimental and Translational Therapeutics (Oxford) - lecturer
- Oxford Clinical Neuroimaging Course (online) - section coordinator and lecturer
- FSL course (international) - co-chair of orgainising committee and faculty
- Alzheimer's Imaging Consortium (AIC) (Alzheimer's Association) pre-conference workshop "Getting started with neuroimaging analysis" (international) - co-organiser and tutor
I am also a College Advisor and Research Member of the Common Room at Kellogg College.
Recent publications
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The lifetime accumulation of multimorbidity and its influence on dementia risk: a UK Biobank Study
Journal article
Patel R. et al, (2024), medRxiv
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Normative models for neuroimaging markers: Impact of model selection, sample size and evaluation criteria.
Journal article
Bozek J. et al, (2023), Neuroimage, 268
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Identifying microstructural changes in diffusion MRI; How to circumvent parameter degeneracy.
Journal article
Rafipoor H. et al, (2022), Neuroimage, 260
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Adults with tetralogy of Fallot show specific features of cerebral small vessel disease: the BACH San Donato study.
Journal article
Melazzini L. et al, (2022), Brain Imaging Behav, 16, 1721 - 1731
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Resting-state, structural and diffusion MRI metrics related to fatigue in MS, MOGAD AND NMOSD
Conference paper
Camera V. et al, (2022), EUROPEAN JOURNAL OF NEUROLOGY, 29, 782 - 783