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Controlling brain activity

Interview about Royal Society Philosophical Transactions special issue on 'Controlling brain activity to alter perception, behaviour and society'

Kristine Krug


Visiting Professor

Prof Kristine Krug investigates the neural basis of visual perception and decision-making. She is an Associate Professor of Neuroscience in the Department of Physiology, Anatomy and Genetics, and the Tutorial Fellow in Biomedical Sciences at Oriel College.

After a DPhil on how ordered maps are formed during brain development, Kristine has been investigating the contribution of single brain cells to visual perception. She held a Dorothy Hodgkin Fellowship of the Royal Society from 2001-2005. Employing ambiguous figures similar to the Necker Cube and 3D images, she characterized not only how V5/MT neurons carry signals directly related to decisions about 3D perception but also showed that the same brain cells may carry signals that are not accessible to perceptual decisions. Her recent work as a Royal Society University Research Fellow demonstrated that neural signals in primate V5/MT contribute causally to perceptual decisions about visual objects formed by combining 3D and motion cues.

The decoding or "read-out" from these neurons is therefore a topic of current research. Her group investigates how contextual factors, like reward and social advice, affect the processing of sensory evidence for decision-making. Another project focusses on the anatomical connections within area V5/MT as well its inter-cortical connections using MRI and histological methods in order to elucidate the neural circuitry that underlies simple perceptual decisions. She also investigates altered decision-making and perception in patients with psychological disorders.

Kristine Krug's work is funded by the Wellcome Trust, the Royal Society, the BBSRC, and the Volkswagen Foundation.

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