Associate Professor of Neurobiology
Esther graduated from the University of Amsterdam cum laude with a MSc degree in Medical Biology in 2000. She then joined the Biomedical and Biological Sciences program at Harvard University, where she performed her PhD training with Azad Bonni. Her work as a graduate student has made significant contributions to our understanding of the specific signaling mechanisms that regulate cell death in the nervous system, particularly in the developing cerebellum. For her graduate studies, Esther was awarded a PhD Fellowship from the Boehringer Ingelheim Fonds and an Albert J. Ryan Foundation Fellowship.
After completing her PhD in 2006, Esther joined Kay Davies’ group in DPAG having been awarded a Human Frontier Science Program Fellowship and later an OXION Training Fellowship. In 2010, Esther was awarded a prestigious Dorothy Hodgkin Research Fellowship from the Royal Society to establish her own research programme in the Department, focussing on the genetic and molecular underpinnings of cerebellar ataxia in mice and humans. Since 2014, she holds a Junior Research Fellowship in Medical Sciences at Wadham College. Esther is also Programme Director of the Oxford Interdisciplinary Bioscience Doctoral Training Partnership.
The Becker group aims to understand the genetic, molecular and cellular mechanisms that underlie neurodevelopmental and neurodegenerative diseases of the cerebellum.
Dulneva A. et al, (2015), Hum Mol Genet, 24, 4114 - 4125
Fogel BL. et al, (2015), Mov Disord, 30, 284 - 286
Becker EB. et al, (2009), Proc Natl Acad Sci U S A, 106, 6706 - 6711
Yuan Z. et al, (2008), Science, 319, 1665 - 1668
Becker EB. and Bonni A., (2006), Neuron, 49, 655 - 662
Recent advances in modelling of cerebellar ataxia using induced pluripotent stem cells
Wong MMK. et al, (2017), Journal of Neurology and Neuromedicine
Wei WC. et al, (2017), J Physiol
Leto K. et al, (2016), Cerebellum, 15, 789 - 828
Marques-Smith A. et al, (2016), Neuron, 89, 536 - 549
Wei WC. et al, (2015), Proc Natl Acad Sci U S A, 112, 10738 - 10743