Research groups
Colleges
Daniel C Anthony
Professor of Experimental Neuropathology
- Fellow of Somerville College
- Honorary Professor, University of Southern Denmark
- Fellow of the British Pharmacological Society
Daniel Anthony, a specialist in inflammatory disease, leads the Experimental Neuropathology Laboratory at the University of Oxford. As a Fellow of Somerville College and an Honorary Professor at the University of Southern Denmark, he has developed a niche in understanding how systemic inflammation influences the outcomes of both acute and chronic brain injuries and infections. His research interests also focus on the role of circulating extracellular vesicles in the pathogenesis of CNS diseases and the contribution of cytokine production to neuropsychiatric disorders.
Professor Anthony's career began with a Ph.D. from University College London in 1994, after which he joined Professor Hugh Perry in Oxford on a British Biotech Fellowship to explore metalloproteinase expression in the CNS. His work has led to the identification of novel biomarkers for diagnosing disease and predicting progression, leveraging a combination of in vivo biology, molecular biology, immunohistochemistry, MRI and PET imaging, and metabolomics. After a stint at the University of Southampton, where he was a Lecturer in Neurobiology, he returned to Oxford in 2004, where he continues to explore the neurobiology of inflammation with research collaborations throughout the world. In 2015, he was awarded a personal Chair in Experimental Neuropathology, and he was made a Fellow of the British Pharmacological Society in 2020.
Recent publications
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Sodium fluoride preserves blood metabolite integrity for biomarker discovery in large-scale, multi-site metabolomics investigations.
Journal article
Xiong W. et al, (2024), Analyst
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Unique pathways downstream of TLR-4 and TLR-7 activation: sex-dependent behavioural, cytokine, and metabolic consequences.
Journal article
Dunstan IK. et al, (2024), Front Cell Neurosci, 18
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Lipopolysaccharide triggers exacerbated microglial activation, excessive cytokine release and behavioural disturbances in mice with truncated Fused-in-Sarcoma Protein (FUS)
Journal article
Trofimov A. et al, (2023), Brain, Behavior, and Immunity - Health, 33
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Leveraging Health Linkage Data From the UK Biobank-With Great Power Comes Great Responsibility.
Journal article
Radford-Smith DE. and Anthony DC., (2023), JAMA Psychiatry
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Serotonin Transporter (SERT) Expression Modulates the Composition of the Western-Diet-Induced Microbiota in Aged Female Mice.
Journal article
Bloemendaal M. et al, (2023), Nutrients, 15