Claire Sexton
BSc (Hons) DPhil
Researcher
- EPA Cephalosporin Junior Research Fellow, Linacre College
My research involves using magnetic resonance imaging (MRI) techniques to study the ageing brain. My doctorate examined structural and functional changes in late-life depression, mild cognitive impairment and Alzheimer’s disease. My current work uses MRI techniques to investigate factors that may promote healthy ageing in the brain, including physical activity and sleep, within the Cognitive Health in Ageing and Whitehall Imaging Oxford research projects.
Photo Credit: Science Oxford
Key publications
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Accelerated changes in white matter microstructure during aging: a longitudinal diffusion tensor imaging study.
Journal article
Sexton CE. et al, (2014), J Neurosci, 34, 15425 - 15436
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Poor sleep quality is associated with increased cortical atrophy in community-dwelling adults.
Journal article
Sexton CE. et al, (2014), Neurology, 83, 967 - 973
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Magnetic resonance imaging in late-life depression: multimodal examination of network disruption.
Journal article
Sexton CE. et al, (2012), Arch Gen Psychiatry, 69, 680 - 689
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A meta-analysis of diffusion tensor imaging in mild cognitive impairment and Alzheimer's disease.
Journal article
Sexton CE. et al, (2011), Neurobiol Aging, 32, 2322.e5 - 2322.18
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A systematic review of diffusion tensor imaging studies in affective disorders.
Journal article
Sexton CE. et al, (2009), Biol Psychiatry, 66, 814 - 823
Recent publications
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Alcohol consumption is associated with reduced creatine levels in the hippocampus of older adults.
Journal article
Demnitz N. et al, (2020), Psychiatry Res Neuroimaging, 295
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Self-reported sleep relates to hippocampal atrophy over the adult lifespan – results from the Lifebrain consortium
Journal article
Fjell AM. et al, (2020), Sleep
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Are People Ready for Personalized Brain Health? Perspectives of Research Participants in the Lifebrain Consortium.
Journal article
Friedman BB. et al, (2019), Gerontologist
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Self-reported sleep relates to hippocampal atrophy across the adult lifespan – results from the Lifebrain consortium
Journal article
Fjell AM. et al, (2019), biorxiv
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Associations between modifiable risk factors and white matter of the aging brain: insights from diffusion tensor imaging studies.
Journal article
Wassenaar TM. et al, (2019), Neurobiol Aging, 80, 56 - 70