Catherine Harmer
DPhil, MA, DipLATHE
Professor of Cognitive Neuroscience
- Research Fellow at Corpus Christi College
I am the director of the Psychopharmacology and Emotional Research Lab (PERL) based at the University Department of Psychiatry in Oxford. This forms a multi-disciplinary team and includes graduate research assistants, DPhil students, post-doctoral researchers, Psychiatrists and Pharmacologists. The research of the group focuses on the psychological mechanisms of antidepressant drug action by exploring drug effects on human models of emotional processing. A range of methodologies are used, including neuropsychological testing, transcranial magnetic stimulation and functional neuroimaging with fMRI and PET in healthy volunteers and patient samples. This research has the potential to integrate psychological and pharmacological views of depression and treatment and has challenged the way in which we typically consider drug treatment for depression to work (see Harmer et al 2009). In addition this research has led to the development of human experimental models to explore the effects of established and novel drugs for the treatment of depression and anxiety. Such results therefore have implications both for how we understand antidepressants to work but also in the identification and development of new treatments for depression and anxiety.
Recent publications
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Human perceptual learning is delayed by the NMDA receptor partial agonist D-cycloserine
Journal article
REINECKE A. et al, (2021), Journal of Psychopharmacology
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Journal article
Hobbs C. et al, (2020), BJPsych Open, 6
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Lithium modulates striatal reward anticipation and prediction error coding in healthy volunteers
Journal article
Inge V. et al, (2020), Neuropsychopharmacology
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Conference paper
DE CATES A. et al, (2020)
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A single administration of the antibiotic, minocycline, reduces fear processing and improves implicit learning in healthy volunteers: analysis of the serum metabolome
Journal article
BURNET P. et al, (2020), Translational Psychiatry