Arjune's primary aim is to revitalise academic epileptology in Oxford. He is interested in cognitive, psychological and psychosocial difficulties in patients with epilepsy. He continues to delineate pathways that may cause neurodegeneration in epilepsy, aiming to develop treatments that may ameliorate both seizures and the co-morbidities that so commonly associate with epilepsy.
Professor of Global Epilepsy
- Consultant Neurologist
- BRC Senior Research Fellow
Arjune trained at the University of Oxford, studying at Corpus Christi College. In his first summer in Oxford he completed a placement with Professor Simon Shorvon at The Institute of Neurology which essentially initiated all that has followed. Having completed an intercalated degree in Physiological Science, including a dissertation with Professor Colin Blakemore, he went to clinical school in Oxford before beginning medical training initially in Oxford and then in London.
In London, Arjune was trained predominantly at The Royal London Hospital and the National Hospital and undertook his PhD with the Department of Clinical and Experimental Epilepsy at Queen Square, sponsored by the MRC and the Guarantors of Brain, studying the molecular basis of neuronal loss in refractory epilepsy. Having completed Specialist Training and a Locum Consultant Posting at The National Hospital, he then went to Sydney during 2012, predominantly to learn to read Video-EEG during an Epilepsy Fellowship with Professor Ernie Somerville.
Arjune is now appointed as Consultant Neurologist at The John Radcliffe Hospital, NIHR BRC Senior Research Fellow in Epileptology and is Head of the Oxford Epilepsy Research Group
Active cortical networks promote shunting fast synaptic inhibition in vivo.
Burman RJ. et al, (2023), Neuron
Analysing patient-generated data to understand behaviours and characteristics of women with epilepsy of childbearing years: A prospective cohort study.
Zhou S-M. et al, (2023), Seizure, 108, 24 - 32
Development and validation of a diagnostic aid for convulsive epilepsy in sub-Saharan Africa: a retrospective case-control study.
Jones GD. et al, (2023), Lancet Digit Health, 5, e185 - e193
Rare Genetic Variation and Outcome of Surgery for Mesial Temporal Lobe Epilepsy
Perucca P. et al, (2023), Annals of Neurology, 93, 752 - 761
Association of Dementia Risk With Focal Epilepsy and Modifiable Cardiovascular Risk Factors.
Tai XY. et al, (2023), JAMA Neurol
Current Major Grants Awarded
'The immunological basis of pharmacoresistance in epilepsy' PIs: Arjune Sen, Sarosh Irani, Julian Knight. Funder: UCB Pharma £1.3M
'Epilepsy Pathway Innovation in Africa (EPInA)' CIs: Charles Newton and Arjune Sen. Funder: NIHR £4.9M