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Publications

Human iPSCs from Aged Donors Retain Their Mitochondrial Aging Signature.

Lejri I. et al, (2024), Int J Mol Sci, 25

Aneuploidy effects on human gene expression across three cell types.

Liu S. et al, (2023), Proc Natl Acad Sci U S A, 120

Lipopolysaccharide distinctively alters human microglia transcriptomes to resemble microglia from Alzheimer's disease mouse models.

Monzón-Sandoval J. et al, (2022), Dis Model Mech, 15

Neurons derived from individual early Alzheimer's disease patients reflect their clinical vulnerability.

Ng B. et al, (2022), Brain Commun, 4

Targeted single-cell RNA sequencing of transcription factors enhances the identification of cell types and trajectories.

Pokhilko A. et al, (2021), Genome Res, 31, 1069 - 1081

Global proteomic analysis of extracellular matrix in mouse and human brain highlights relevance to cerebrovascular disease.

Pokhilko A. et al, (2021), J Cereb Blood Flow Metab

TRESK is a key regulator of nocturnal suprachiasmatic nucleus dynamics and light adaptive responses.

Lalic T. et al, (2020), Nat Commun, 11

Targeted RNA sequencing enhances gene expression profiling of ultra-low input samples

CADER M. et al, (2020), RNA Biology

Patient fibroblast circadian rhythms predict lithium sensitivity in bipolar disorder.

Sanghani HR. et al, (2020), Mol Psychiatry

Common transcriptional signatures of neuropathic pain.

Pokhilko A. et al, (2020), Pain

The genetics of migraine and the path to precision medicine.

Cader MZ., (2020), 255, 403 - 418

High glucose concentrations mask cellular phenotypes in a stem cell model of tuberous sclerosis complex.

Rocktäschel P. et al, (2019), Epilepsy Behav, 101

A causal role for TRESK loss of function in migraine mechanisms.

Pettingill P. et al, (2019), Brain

IHC 2019 Author index

O'connor E. et al, (2019), CEPHALALGIA, 39, 1 - 1

Using longitudinal real-world electronic healthcare records to study long-term outcomes in headache sufferers.

Nash A. et al, (2019), CEPHALALGIA, 39, 43 - 43

Proteolytic shedding of the prion protein via activation of metallopeptidase ADAM10 reduces cellular binding and toxicity of amyloid-β oligomers.

Jarosz-Griffiths HH. et al, (2019), J Biol Chem, 294, 7085 - 7097

Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease.

Fang EF. et al, (2019), Nat Neurosci, 22, 401 - 412

Culprit or Bystander: Defective Mitophagy in Alzheimer's Disease.

Xie C. et al, (2019), Front Cell Dev Biol, 7

The Role of TRESK in Discrete Sensory Neuron Populations and Somatosensory Processing.

Weir GA. et al, (2019), Front Mol Neurosci, 12

Reproducibility of Molecular Phenotypes after Long-Term Differentiation to Human iPSC-Derived Neurons: A Multi-Site Omics Study.

Volpato V. et al, (2018), Stem Cell Reports, 11, 897 - 911

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