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Publications

Identification of a possible proteomic biomarker in Parkinson's disease: discovery and replication in blood, brain and cerebrospinal fluid.

Winchester L. et al, (2023), Brain Commun, 5

Neurons derived from individual early Alzheimer's disease patients reflect their clinical vulnerability.

Ng B. et al, (2022), Brain Commun, 4

Dysregulated Fc gamma receptor-mediated phagocytosis pathway in Alzheimer's disease: network-based gene expression analysis.

Park YH. et al, (2020), Neurobiol Aging, 88, 24 - 32

Tau pathology in early Alzheimer’s disease is linked to selective disruptions in neurophysiological network dynamics

Kocagoncu E. et al, (2020), Neurobiology of Aging

Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery Cohort.

Westwood S. et al, (2020), J Alzheimers Dis, 74, 213 - 225

Will We Have a Drug for Alzheimer's Disease by 2030? The View From Pharma.

Lovestone S. and Manji HK., (2020), Clin Pharmacol Ther, 107, 79 - 81

Minocycline at 2 Different Dosages vs Placebo for Patients With Mild Alzheimer Disease: A Randomized Clinical Trial.

Howard R. et al, (2019), JAMA Neurol

Genetic and Real-World Clinical Data, Combined with Empirical Validation, Nominate Jak-Stat Signaling as a Target for Alzheimer's Disease Therapeutic Development.

Nevado-Holgado AJ. et al, (2019), Cells, 8

A plasma protein classifier for predicting amyloid burden for preclinical Alzheimer's disease.

Ashton NJ. et al, (2019), Sci Adv, 5

MRI predictors of amyloid pathology: results from the EMIF-AD Multimodal Biomarker Discovery study.

Ten Kate M. et al, (2018), Alzheimers Res Ther, 10

Cross-sectional and longitudinal analyses of outdoor air pollution exposure and cognitive function in UK Biobank.

Cullen B. et al, (2018), Sci Rep, 8

Heterogeneous patterns of brain atrophy in Alzheimer's disease.

Poulakis K. et al, (2018), Neurobiol Aging, 65, 98 - 108

Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology.

Smith RG. et al, (2018), Alzheimers Dement

Imaging Aβ and tau in early stage Alzheimer's disease with [18F]AV45 and [18F]AV1451.

Firouzian A. et al, (2018), EJNMMI Res, 8

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.

Pardiñas AF. et al, (2018), Nat Genet, 50, 381 - 389

Alzheimer's disease in humans and other animals: A consequence of postreproductive life span and longevity rather than aging.

Gunn-Moore D. et al, (2018), Alzheimers Dement, 14, 195 - 204

A Decade of Blood Biomarkers for Alzheimer's Disease Research: An Evolving Field, Improving Study Designs, and the Challenge of Replication.

Shi L. et al, (2018), J Alzheimers Dis, 62, 1181 - 1198

Clusterin Is Required for β-Amyloid Toxicity in Human iPSC-Derived Neurons.

Robbins JP. et al, (2018), Front Neurosci, 12

Gait in Mild Alzheimer's Disease: Feasibility of Multi-Center Measurement in the Clinic and Home with Body-Worn Sensors: A Pilot Study.

Mc Ardle R. et al, (2018), J Alzheimers Dis, 63, 331 - 341

Design, synthesis and evaluation in an LPS rodent model of neuroinflammation of a novel 18F-labelled PET tracer targeting P2X7.

Fantoni ER. et al, (2017), EJNMMI Res, 7

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