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Transcription-dependent DNA double-strand breaks and human disease.

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Cristini A. et al, (2020), Mol Cell Oncol, 7

N6-methyladenosine regulates the stability of RNA:DNA hybrids in 1human cells

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GROMAK N., (2019), Nature Genetics

Senataxin: Genome Guardian at the Interface of Transcription and Neurodegeneration.

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Groh M. et al, (2017), J Mol Biol, 429, 3181 - 3195

Increased global transcription activity as a mechanism of replication stress in cancer.

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Kotsantis P. et al, (2016), Nat Commun, 7

Out of balance: R-loops in human disease.

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Groh M. and Gromak N., (2014), PLoS Genet, 10

Mechanisms of transcriptional dysregulation in repeat expansion disorders.

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Groh M. et al, (2014), Biochem Soc Trans, 42, 1123 - 1128

Drosha Regulates Gene Expression Independently of RNA Cleavage Function.

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Gromak N. et al, (2014), Cell Rep, 7, 1753 - 1754

Drosha regulates gene expression independently of RNA cleavage function.

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Gromak N. et al, (2013), Cell Rep, 5, 1499 - 1510

Intronic microRNAs: a crossroad in gene regulation.

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Gromak N., (2012), Biochem Soc Trans, 40, 759 - 761

Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing.

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Webby CJ. et al, (2009), Science, 325, 90 - 93

Primary microRNA transcripts are processed co-transcriptionally.

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Morlando M. et al, (2008), Nat Struct Mol Biol, 15, 902 - 909

Primary microRNA transcripts are processed co-transcriptionally.

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Morlando M. et al, (2008), Nat Struct Mol Biol

Modulating alternative splicing by cotranscriptional cleavage of nascent intronic RNA.

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Gromak N. et al, (2008), RNA, 14, 359 - 366

Pause sites promote transcriptional termination of mammalian RNA polymerase II.

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Gromak N. et al, (2006), Mol Cell Biol, 26, 3986 - 3996

Exon tethering in transcription by RNA polymerase II.

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Dye MJ. et al, (2006), Mol Cell, 21, 849 - 859

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