Mutant huntingtin induces neuronal apoptosis via derepressing the non-canonical poly(A) polymerase PAPD5.
Chen ZS. et al, (2025), Nat Commun, 16
Asymmetry in amyotrophic lateral sclerosis: clinical, neuroimaging and histological observations.
Yoganathan K. et al, (2025), Brain
Drug repurposing in amyotrophic lateral sclerosis (ALS).
Carroll E. et al, (2025), Expert Opin Drug Discov, 1 - 18
The Basis of Cognitive and Behavioral Dysfunction in Amyotrophic Lateral Sclerosis.
Bampton A. et al, (2024), Brain Behav, 14
Cellular and axonal transport phenotypes due to the C9ORF72 HRE in iPSC motor and sensory neurons.
Scaber J. et al, (2024), Stem Cell Reports, 19, 957 - 972
Recent insights from human induced pluripotent stem cell models into the role of microglia in amyotrophic lateral sclerosis.
Nikel LM. et al, (2024), Bioessays
An ALS-associated mutation dysregulates microglia-derived extracellular microRNAs in a sex-specific manner.
Christoforidou E. et al, (2024), Dis Model Mech, 17
Venous thromboembolism risk in amyotrophic lateral sclerosis: a hospital record-linkage study.
Goldacre R. et al, (2024), J Neurol Neurosurg Psychiatry
Dyspnea (breathlessness) in amyotrophic lateral sclerosis/motor neuron disease: prevalence, progression, severity, and correlates.
Young CA. et al, (2024), Amyotroph Lateral Scler Frontotemporal Degener, 1 - 11
Improving the measurement properties of the Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised (ALSFRS-R): deriving a valid measurement total for the calculation of change.
Young CA. et al, (2024), Amyotroph Lateral Scler Frontotemporal Degener, 1 - 10
Mutant GGGGCC RNA prevents YY1 from binding to Fuzzy promoter which stimulates Wnt/β-catenin pathway in C9ALS/FTD.
Chen ZS. et al, (2023), Nat Commun, 14
C9orf72-ALS human iPSC microglia are pro-inflammatory and toxic to co-cultured motor neurons via MMP9.
Vahsen BF. et al, (2023), Nat Commun, 14
PRMT inhibitor promotes SMN2 exon 7 inclusion and synergizes with nusinersen to rescue SMA mice.
Kordala AJ. et al, (2023), EMBO Mol Med
Aberrant dynein function promotes TDP-43 aggregation and upregulation of p62 in male mice harboring transgenic human TDP-43.
Christoforidou E. et al, (2023), Amyotroph Lateral Scler Frontotemporal Degener, 1 - 10
Advantages of routine next-generation sequencing over standard genetic testing in the amyotrophic lateral sclerosis clinic.
Scaber J. et al, (2023), Eur J Neurol
A survey of current practice in genetic testing in amyotrophic lateral sclerosis in the UK and Republic of Ireland: implications for future planning.
De Oliveira HM. et al, (2022), Amyotroph Lateral Scler Frontotemporal Degener, 1 - 9
Profiling non-coding RNA expression in cerebrospinal fluid of amyotrophic lateral sclerosis patients.
Joilin G. et al, (2022), Ann Med, 54, 3069 - 3078