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Publications

Childhood body size directly increases type 1 diabetes risk based on a lifecourse Mendelian randomization approach

Richardson TG. et al, (2022), Nature Communications, 13

Low-dose IL-2 reduces IL-21+ T cell numbers and induces anti-inflammatory gene expression in type 1 diabetes

Zhang J. et al, (2022), Nature Communications

Detection of enterovirus RNA in peripheral blood mononuclear cells correlates with the presence of the predisposing allele of the type 1 diabetes risk gene IFIH1 and with disease stage.

Sioofy-Khojine A-B. et al, (2022), Diabetologia

An open approach to systematically prioritize causal variants and genes at all published human GWAS trait-associated loci.

Mountjoy E. et al, (2021), Nat Genet, 53, 1527 - 1533

Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes.

Robertson CC. et al, (2021), Nat Genet

Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Collier DA. et al, (2021), Nature, 593, 136 - 141

SARS-CoV-2 within-host diversity and transmission

Lythgoe KA. et al, (2021), Science (New York, N.Y.), 372

Analysis of overlapping genetic association in type 1 and type 2 diabetes.

Inshaw JRJ. et al, (2021), Diabetologia

SARS-CoV-2 within-host diversity and transmission.

Lythgoe KA. et al, (2021), Science

Open Targets Genetics: systematic identification of trait-associated genes using large-scale genetics and functional genomics.

Ghoussaini M. et al, (2021), Nucleic Acids Res, 49, D1311 - D1320

Circulating C-peptide levels mirror patterns of residual beta cell mass in the pancreas of children and young people with type 1 diabetes

Carr ALJ. et al, (2020), DIABETOLOGIA, 63, S132 - S133

Publisher Correction: Whole-genome sequencing of a sporadic primary immunodeficiency cohort.

Thaventhiran JED. et al, (2020), Nature, 584

CD70 expression determines the therapeutic efficacy of expanded human regulatory T cells.

Arroyo Hornero R. et al, (2020), Commun Biol, 3

Whole-genome sequencing of a sporadic primary immunodeficiency cohort.

Thaventhiran JED. et al, (2020), Nature, 583, 90 - 95

Whole-genome sequencing of patients with rare diseases in a national health system.

Turro E. et al, (2020), Nature, 583, 96 - 102

Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis.

Trzupek D. et al, (2020), Genome Med, 12

Author Correction: Approaches and advances in the genetic causes of autoimmune disease and their implications.

Inshaw JRJ. et al, (2020), Nat Immunol, 21

Assessing the effect of closed-loop insulin delivery from onset of type 1 diabetes in youth on residual beta-cell function compared to standard insulin therapy (CLOuD study): a randomised parallel study protocol.

Boughton C. et al, (2020), BMJ Open, 10

Genetic Variants Predisposing Most Strongly to Type 1 Diabetes Diagnosed Under Age 7 Years Lie Near Candidate Genes That Function in the Immune System and in Pancreatic β-Cells.

Inshaw JRJ. et al, (2020), Diabetes Care, 43, 169 - 177

Interleukin-2 Therapy of Autoimmunity in Diabetes (ITAD): a phase 2, multicentre, double-blind, randomized, placebo-controlled trial.

Marcovecchio ML. et al, (2020), Wellcome Open Res, 5

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