Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Publications

KATP Channels and the Metabolic Regulation of Insulin Secretion in Health and Disease: The 2022 Banting Medal for Scientific Achievement Award Lecture

Ashcroft FM., (2023), Diabetes, 72, 693 - 702

Glucokinase activity in diabetes: too much of a good thing?

Ashcroft FM. et al, (2022), Trends Endocrinol Metab

Altered glycolysis triggers impaired mitochondrial metabolism and mTORC1 activation in diabetic β-cells.

Haythorne E. et al, (2022), Nat Commun, 13

The dynamic interplay of PIP2 and ATP in the regulation of the KATP channel.

Pipatpolkai T. et al, (2022), J Physiol

Monitoring glycolytic dynamics in single cells using a fluorescent biosensor for fructose 1,6-bisphosphate.

Koberstein JN. et al, (2022), Proc Natl Acad Sci U S A, 119

Dissection-independent production of Plasmodium sporozoites from whole mosquitoes.

Blight J. et al, (2021), Life Sci Alliance, 4

The KCNJ11-E23K Gene Variant Hastens Diabetes Progression by Impairing Glucose-Induced Insulin Secretion.

Sachse G. et al, (2021), Diabetes, 70, 1145 - 1156

Voices: Insulin and beyond

Roth J. et al, (2021), Cell Metabolism, 33, 692 - 699

Measuring Nucleotide Binding to Intact, Functional Membrane Proteins in Real Time.

Usher SG. et al, (2021), J Vis Exp

Metabolic regulation of insulin secretion in health and disease

Haythorne E. and Ashcroft FM., (2021), Biochemist, 43, 4 - 8

Evaluating inositol phospholipid interactions with inward rectifier potassium channels and characterising their role in disease

Pipatpolkai T. et al, (2020), Communications Chemistry, 3

New insights into KATP channel gene mutations and neonatal diabetes mellitus.

Pipatpolkai T. et al, (2020), Nat Rev Endocrinol

Nucleotide inhibition of the pancreatic ATP-sensitive K+ channel explored with patch-clamp fluorometry.

Usher SG. et al, (2020), Elife, 9

Erratum. Fetal Macrosomia and Neonatal Hyperinsulinemic Hypoglycemia Associated With Transplacental Transfer of Sulfonylurea in a Mother With KCNJ11-Related Neonatal Diabetes. Diabetes Care 2014;37:3333-3335

Myngheer N. et al, (2019), Diabetes care, 42

Tamoxifen administration in pregnant mice can be deleterious to both mother and embryo.

Ved N. et al, (2019), Lab Anim

Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells.

Haythorne E. et al, (2019), Nat Commun, 10

Correction to: Q&A: insulin secretion and type 2 diabetes: why do β-cells fail?

Cantley J. and Ashcroft FM., (2019), BMC Biol, 17

Correction: Systemic administration of glibenclamide fails to achieve therapeutic levels in the brain and cerebrospinal fluid of rodents (PLoS ONE (2015) 10: 7 (e0134476) DOI: 10.1371/journal.pone.0134476)

Lahmann C. et al, (2019), PLoS ONE, 14

Hyperglycaemia adversely affects mitochondrial function in pancreatic islets

Haythorne E. et al, (2019), DIABETIC MEDICINE, 36, 37 - 37

Activation mechanism of ATP-sensitive K+ channels explored with real-time nucleotide binding.

Puljung M. et al, (2019), Elife, 8

Load More

1
2
3
4
5
6
7
...
»

Include forthcoming?