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Publications

An ALS-linked mutation in TDP-43 disrupts normal protein interactions in the motor neuron response to oxidative stress.

Feneberg E. et al, (2020), Neurobiol Dis, 144

Mice Carrying ALS Mutant TDP-43, but Not Mutant FUS, Display In Vivo Defects in Axonal Transport of Signaling Endosomes.

Sleigh JN. et al, (2020), Cell Rep, 30, 3655 - 3662.e2

Neuronal over-expression of Oxr1 is protective against ALS-associated mutant TDP-43 mislocalisation in motor neurons and neuromuscular defects in vivo.

Williamson MG. et al, (2019), Hum Mol Genet, 28, 3584 - 3599

The interactome of human TDP-43 in a cellular model of amyotrophic lateral sclerosis

Feneberg E. et al, (2019), EUROPEAN JOURNAL OF NEUROLOGY, 26, 221 - 222

Single-copy expression of an amyotrophic lateral sclerosis-linked TDP-43 mutation (M337V) in BAC transgenic mice leads to altered stress granule dynamics and progressive motor dysfunction.

Gordon D. et al, (2019), Neurobiol Dis, 121, 148 - 162

Absence of wide-spread mis-splicing in the preclinical phase of a native promoter driven TDP-43 mouse model of ALS

Scaber J. et al, (2016), EUROPEAN JOURNAL OF NEUROLOGY, 23, 797 - 797

TDP-43 is cytoplasmically mislocalized and associated with impaired stress responses and survival of primary neurons from symptomatic amyotrophic lateral sclerosis (ALS) mice

Farrimond L. et al, (2016), EUROPEAN JOURNAL OF NEUROLOGY, 23, 390 - 391

Absence of wide-spread mis-splicing in the preclinical phase of a native promoter driven TDP-43 mouse model of ALS

Scaber J. et al, (2016), NEUROMUSCULAR DISORDERS, 26, S31 - S31

TARDBP pathogenic mutations increase cytoplasmic translocation of TDP-43 and cause reduction of endoplasmic reticulum Ca²⁺ signaling in motor neurons.

Mutihac R. et al, (2015), Neurobiol Dis, 75, 64 - 77

Motor disorders

Gordon D. and Talbot K., (2014), Behavioral Genetics of the Mouse Volume II: Genetic Mouse Models of Neurobehavioral Disorders, 63 - 78

Include forthcoming?