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Proton transfer into and out of proteins is important, both for many enzyme reaction mechanisms and proton pumping across membranes. Recent work on several proteins has revealed stringent requirements for amino-acid side chains and subtle reorganisation of hydrogen-bond networks involving bound water molecules.

Type

Journal article

Journal

Curr Biol

Publication Date

07/09/2000

Volume

10

Pages

R627 - R630

Keywords

Hydrogen-Ion Concentration, Kinetics, Proteins, Protons