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Transformation of mutant yeast cells by cloned genomic DNA from a higher eukaryote has made it possible to isolate a Drosophila DNA sequence that complements a yeast adenine-8-mutation. A 0.8-kilobase poly(A)-containing RNA is transcribed from the cloned Drosophila segment in transformed yeast cells and can account for functional expression of the gene.


Journal article



Publication Date





33 - 37


Adenine, Animals, DNA Restriction Enzymes, Drosophila melanogaster, Genes, Genetic Complementation Test, Nucleic Acid Hybridization, Plasmids, Saccharomyces cerevisiae, Transcription, Genetic, Transformation, Genetic