Molecular pathomechanisms of Alzheimer's disease
Penke B., Datki Z., Hetényi C., Molnár Z., Lengyel I., Soós K., Zarándi M.
β-Amyloids are neurotoxic compounds produced in the brain and cause Alzheimer-type senile dementia. Their toxicity is in good correlation with their aggregation properties. Short peptide fragments of β-amyloid prevent Aβ-toxicity, probably by binding on the Aβ-aggregate surface. © 2003 Elsevier B.V. All rights reserved.