Controversies in epilepsy: debates held during the Fourth International Workshop on Seizure Prediction.
Frei MG., Zaveri HP., Arthurs S., Bergey GK., Jouny CC., Lehnertz K., Gotman J., Osorio I., Netoff TI., Freeman WJ., Jefferys J., Worrell G., Quyen MLV., Schiff SJ., Mormann F.
Debates on six controversial topics were held during the Fourth International Workshop on Seizure Prediction (IWSP4) convened in Kansas City, KS, USA, July 4-7, 2009. The topics were (1) Ictogenesis: Focus versus Network? (2) Spikes and Seizures: Step-relatives or Siblings? (3) Ictogenesis: A Result of Hyposynchrony? (4) Can Focal Seizures Be Caused by Excessive Inhibition? (5) Do High-Frequency Oscillations Provide Relevant Independent Information? (6) Phase Synchronization: Is It Worthwhile as Measured? This article, written by the IWSP4 organizing committee and the debaters, summarizes the arguments presented during the debates.