Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

The mouse genome contains 50 copies of a long complex repeat unit localized as a repeat sequence island to the A3 Giemsa-positive (dark) band on the mouse X chromosome. The repeat units are not tandemly arranged but are juxtaposed and inserted by unrelated sequences of high repetition. The repeat sequence island possesses two notable features that have been suggested as diagnostic features of mammalian Giemsa-positive bands. First, the repeat sequence island encompasses a 1-megabase region devoid of CpG islands; second, it features a high concentration of L1 long interspersed repeat sequences.

Original publication




Journal article


Proc Natl Acad Sci U S A

Publication Date





399 - 403


Animals, Blotting, Southern, Chromosome Banding, Chromosome Mapping, Cloning, Molecular, Crosses, Genetic, DNA, Dinucleoside Phosphates, Female, Gene Library, Male, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Muridae, Repetitive Sequences, Nucleic Acid, Restriction Mapping, Thymus Gland, X Chromosome