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A nitric oxide delivery system for adult ventilators has been developed; this is designed to maintain a constant inspired nitric oxide concentration of 16 volumes per million (vpm) in spite of changes in minute and tidal volumes. In a laboratory test the system maintained tracer gas concentrations equivalent to nitric oxide 13.8-18 vpm for tidal volumes of 500, 700 and 900 ml, ventilator rates of 10, 15 and 20 b.p.m., peak inspiratory flow rates of 30, 40 and 50 litre min-1 and square, sine and decelerating ramp flow profiles.


Journal article


Br J Anaesth

Publication Date





700 - 702


Adult, Anesthesia, Inhalation, Carbon Dioxide, Equipment Design, Equipment Safety, Humans, Nitric Oxide, Pulmonary Ventilation, Tidal Volume, Ventilators, Mechanical