Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Rhodobacter sphaeroides has a complex chemosensory system, with several loci encoding multiple homologues of the components required for chemosensing in Escherichia coli. The operons cheOp2 and cheOp3 each encode complete pathways, and both are essential for chemosensing. The components of cheOp2 are predominantly localized to the cell pole, whereas those encoded by cheOp3 are predominantly targeted to a discrete cluster in the cytoplasm. Here we show that the expression of the two pathways is regulated independently. Overlapping promoters recognized by sigma(28) and sigma(70) RNAP holoenzyme transcribe cheOp2, whereas cheOp3 is regulated by one of the four sigma(54) homologues, RpoN3. The different regulation of these operons may reflect the need for balancing responses to extra- and intracellular signals under different growth conditions.

Original publication

DOI

10.1128/JB.00964-06

Type

Journal article

Journal

J Bacteriol

Publication Date

11/2006

Volume

188

Pages

7932 - 7940

Keywords

Bacterial Proteins, Base Sequence, Chemotaxis, DNA-Directed RNA Polymerases, Gene Expression Regulation, Bacterial, Molecular Sequence Data, Operon, Promoter Regions, Genetic, RNA Polymerase Sigma 54, Rhodobacter sphaeroides, Sigma Factor, Transcription Initiation Site