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The recent discovery of tumour necrosis factor has been a major advance in the understanding of the biology of the immunological system. A review of this macrophage-secreted polypeptide hormone may be of special interest to clinicians because it appears to play a role in several important disease processes and holds considerable promise as a therapeutic tool.

Type

Journal article

Journal

S Afr Med J

Publication Date

15/10/1988

Volume

74

Pages

411 - 417

Keywords

Animals, Humans, Mice, Tumor Necrosis Factor-alpha