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Recent studies have uncovered new connections between the enzymes of mRNA 3' end processing and RNA polymerase II. These connections improve the efficiency of polyadenylation and signal to the polymerase to terminate transcription; their discovery reveals another level of gene regulation.

Type

Journal article

Journal

Curr Biol

Publication Date

23/12/2002

Volume

12

Pages

R855 - R857

Keywords

Cleavage Stimulation Factor, Macromolecular Substances, Polyadenylation, Protein Structure, Tertiary, RNA Polymerase II, RNA Processing, Post-Transcriptional, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Schizosaccharomyces, Transcription Factors, mRNA Cleavage and Polyadenylation Factors