Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

The inherited disorders of hemoglobin represent the most common monogenic diseases. This article provides a brief description of the main inherited disorders of hemoglobin and their classification, and summarizes progress made in the last decade toward a better awareness and recognition of these disorders as a global health problem. Also presented are the main demographic, genetic, and environmental factors that influence the present and future health burden of these disorders. The strengths and limitations of existing estimates and current health policies in high-, low-, and middle-income countries are discussed.

Original publication




Journal article


Hematol Oncol Clin North Am

Publication Date





327 - 341


Consanguinity, Genetic disease, Human migrations, Malaria selection, Newborn screening, Public health, Sickle cell disease, Thalassemias, Cost of Illness, Developing Countries, Global Health, Hemoglobinopathies, Humans, Risk Factors