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We report the first published case study of a suddenly occurring panic attack in a patient with no prior history of panic disorder during combined functional magnetic resonance imaging (fMRI, 1.5 Tesla) and electrocardiogram (ECG) recording. The single case was a 46-year-old woman who developed a panic attack near the planned end of the fMRI acquisition session, which therefore had to be aborted. Correlational analysis of heart rate fluctuations and fMRI data revealed a significant negative association in the left middle temporal gyrus. Additionally, regions-of-interest (ROI) analyses indicated significant positive associations in the left amygdala, and trends towards significance in the right amygdala and left insula.

Original publication

DOI

10.1080/13554790903066909

Type

Journal article

Journal

Neurocase

Publication Date

12/2009

Volume

15

Pages

527 - 534

Keywords

Brain, Brain Mapping, Electrocardiography, Female, Heart, Heart Rate, Humans, Magnetic Resonance Imaging, Middle Aged, Panic Disorder, Regression Analysis, Restless Legs Syndrome, Signal Processing, Computer-Assisted, Time Factors, Visual Perception