127 Early manifestations of diabetic cardiomyopathy assessed by cardiac magnetic resonance imaging and spectroscopy.
Levelt E., Ntusi N., Mahmod M., Wainwright C., Piechnik S., Francis J., Davis A., Schneider J., Leeson P., Karamitsos T., Holloway C., Clarke K., Neubauer S.
Large, population based studies have shown that diabetes mellitus (DM) of long durationis associated with increased incidence of heart failure, independent of underlying hypertension and coronary artery disease. Cardiovascular magnetic resonance imaging (CMR) and magnetic resonance spectroscopy (MRS) provide comprehensive, non-invasive, multiparametric measures of the functional, structural and metabolic status of the heart. We used magnetic resonance imaging and spectroscopy to determine whether subclinical functional, structural and metabolic alterations occur in a patient cohort of early-onset, type 2 DM.