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Many mouse models of neoplasia and pre-neoplasia require the examination of whole mounts of the gastrointestinal tract. A simple device has been produced to facilitate the rapid preparation of mouse intestines for subsequent quantification of tumours and pre-neoplastic lesions such as aberrant crypt foci. The device greatly speeds up the production of whole mounts and also provides far more consistent and better-quality preparations.

Original publication

DOI

10.1111/j.1365-2184.2006.00391.x

Type

Journal article

Journal

Cell Prolif

Publication Date

10/2006

Volume

39

Pages

415 - 420

Keywords

Adenomatous Polyposis Coli, Animals, Colon, Colonic Neoplasms, Colonic Polyps, Equipment Design, Histological Techniques, Intestine, Small, Intestines, Mice, Precancerous Conditions