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BACKGROUND: Massive ipsilateral edema in patients with cerebral dural arteriovenous fistula (DAVF) is poorly documented. The present study better characterizes this condition through assessment of venous anatomy and potential underlying mechanisms. METHODS: One hundred and two consecutive patients diagnosed with DAVF and admitted to the Huashan Hospital from 2006 to 2012 were retrospectively reviewed for the clinical and radiologic data, and those with ipsilateral edema were recruited. An edema scale was calculated from the locations with edema on magnetic resonance imaging. We created a reflux anatomic venous scale (RAVS, including veins of Labbe, Sylvian, and Troland) based on DSA. Two experienced interventional neuroradiologists independently assessed the images and then reached consensus. The Spearman nonparametric rank correlation was performed to analyze the correlation between edema scale and RAVS. RESULTS: Seven patients (mean 61 ± 13 years; 4 men:3 women) with ipsilateral intracranial edema were finally included. DAVF in transverse sinus with reflux flow initially in vein of the Labbe was seen in all patients. Increased edema scale was significantly correlated with increased RAVS (Spearman rho = .856, P = .014). CONCLUSION: The present study indicated that severe ipsilateral edema, with reflux flow initially in vein of the Labbe, was associated with the increased number of reflux anatomic veins in transverse sinus DAVF.

Original publication

DOI

10.1016/j.jstrokecerebrovasdis.2013.09.016

Type

Journal article

Journal

J Stroke Cerebrovasc Dis

Publication Date

05/2014

Volume

23

Pages

1094 - 1098

Keywords

DAVF, anatomic veins, edema, reflux flow, Aged, Angiography, Digital Subtraction, Brain Edema, Central Nervous System Vascular Malformations, Cerebral Angiography, Cerebral Veins, Cerebrovascular Circulation, Female, Humans, Male, Middle Aged, Phlebography, Predictive Value of Tests, Retrospective Studies, Risk Factors, Severity of Illness Index