Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

In both animal and plant kingdoms, body size is a fundamental but still poorly understood attribute of biological systems. Here we report that the Arabidopsis NAC transcription factor 'Regulator of Proteasomal Gene Expression' (RPX) controls leaf size by positively modulating proteasome activity. We further show that the cis-element recognized by RPX is evolutionarily conserved between higher plant species. Upon over-expression of RPX, plants exhibit reduced growth, which may be reversed by a low concentration of the pharmacological proteasome inhibitor MG132. These data suggest that the rate of protein turnover during growth is a critical parameter for determining final organ size.

Original publication

DOI

10.1111/tpj.12097

Type

Journal article

Journal

Plant J

Publication Date

04/2013

Volume

74

Pages

25 - 36

Keywords

Arabidopsis, Arabidopsis Proteins, DNA, Bacterial, Gene Expression Regulation, Plant, Gene Knockout Techniques, Gene Regulatory Networks, Leupeptins, Mutagenesis, Insertional, Plant Leaves, Plant Roots, Plants, Genetically Modified, Promoter Regions, Genetic, Proteasome Endopeptidase Complex, Transcription Factors