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Gravitational forces may lead to local changes in subarachnoid cerebrospinal fluid (CSF) layer thickness, which has important implications for neurophysiological modulation and recording techniques. This study examines the effect of gravitational pull associated with different head positions on the distribution of subarachnoid CSF using structural magnetic resonance imaging. Images of seven subjects in three different positions (supine, left lateral and prone) were statistically compared. Results suggest that subarachnoid CSF volume decreases on the side of the head closest to the ground, due to downward brain movement with gravity. These findings warrant future research into currently unexplored gravitation-induced changes in regional subarachnoid CSF thickness.

Original publication




Journal article


Physiol Meas

Publication Date





N9 - N14


Adult, Cerebrospinal Fluid, Female, Head, Humans, Magnetic Resonance Imaging, Male, Movement, Nervous System Physiological Phenomena, Subarachnoid Space