Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

OBJECTIVE: We investigate the implications of high magnetic field strength on MR venography based on susceptibility-weighted imaging (SWI) and estimate the optimum echo time to obtain maximum contrast between blood and brain tissue. MATERIALS AND METHODS: We measured tissue contrast and T2* relaxation times at 7 T of gray matter, white matter, and venous blood in vivo. RESULTS: T2* relaxation times of gray matter, white matter, and venous blood in vivo yielded 32.9 +/- 2.3, 27.7 +/- 4.3, and 7.4 +/- 1.4 ms, respectively. Optimum TE was found to be 15 ms which is supported by theoretical considerations. Using this optimum TE, we acquired 3D high resolution datasets with a large volume coverage in a short measurement time that show very detailed microanatomical structures of the human brain such as intracortical veins and laminar cortical substructures. CONCLUSIONS: By applying optimised vessel filters (vesselness filter and vessel enhancing diffusion) whole brain MR venograms can be obtained at 7 T with a significantly reduced measurement time compared to 3 T.

Original publication

DOI

10.1007/s10334-007-0101-3

Type

Journal article

Journal

MAGMA

Publication Date

03/2008

Volume

21

Pages

149 - 158

Keywords

Brain, Brain Mapping, Computer Simulation, Diagnostic Imaging, Electromagnetic Fields, Equipment Design, Filtration, Humans, Magnetic Resonance Imaging, Models, Statistical, Phlebography, Time Factors