Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Evidence-based medicine is often seen as something dry, formal, and statistical, often used to justify a proscriptive approach to medicine. A more attractive approach is to use our understanding of those aspects of studies that can mislead us to identify the evidence we can trust. Evidence can, and probably should, be based on patient-centred outcomes of importance to clinical practice. The particular issues differ somewhat between clinical trials, observational studies, adverse events, diagnosis, and health economics. Here we explore some of important criteria relating to evidence from randomised trials, either alone or in meta-analyses.

Original publication




Journal article


European Journal of Hospital Pharmacy

Publication Date





507 - 509