Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Regulated intramembrane proteolysis (RIP) has recently emerged as a conserved mechanism for controlling many signalling pathways in both prokaryotes and eukaryotes. Although early examples were confined to the activation of membrane-tethered transcription factors in the cell receiving the signal, recent analysis indicates that RIP also regulates the emission of factors involved in intercellular communication.

Type

Journal article

Journal

Curr Opin Genet Dev

Publication Date

10/2002

Volume

12

Pages

512 - 518

Keywords

Active Transport, Cell Nucleus, Animals, Cell Communication, Cell Nucleus, Cysteine Endopeptidases, Cytoplasm, Endopeptidases, Evolution, Molecular, Humans, Intracellular Membranes, Multienzyme Complexes, Proteasome Endopeptidase Complex, Signal Transduction, Transcription Factors