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The retina provides an example of a fundamental property of developing cells: cell fate decisions are stable. A recent paper reports a double negative feedback loop that leads to bistable fate decisions in the colour-detecting photoreceptors of Drosophila.

Original publication

DOI

10.1016/j.cub.2005.10.062

Type

Journal article

Journal

Curr Biol

Publication Date

22/11/2005

Volume

15

Pages

R924 - R926

Keywords

Animals, Cell Differentiation, Color Perception, Drosophila, Drosophila Proteins, Feedback, Physiological, Gene Expression Regulation, Developmental, Intracellular Signaling Peptides and Proteins, Photoreceptor Cells, Invertebrate, Protein Kinases, Rhodopsin