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51 patients with depressive episode (40--recurrent depressive disorder, 11--bipolar affective disorder) were treated by the clomipramine intravenous infusions. The number of infusions varied from 5 to 21 (mostly 10-16). The median of maximal dose was 150 mg. There were significant clinical improvement measured by CGI. The therapy was well tolerated.


Journal article


Psychiatr Pol

Publication Date





85 - 91


Adult, Antidepressive Agents, Tricyclic, Bipolar Disorder, Clomipramine, Depressive Disorder, Dose-Response Relationship, Drug, Female, Humans, Infusions, Intravenous, Male, Middle Aged, Retrospective Studies, Serotonin Uptake Inhibitors, Time Factors, Treatment Outcome