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Recent reports have substantiated claims that the clinical spectrum of falciparum malaria is different in African children as compared with nonimmune adults. The SPf66 vaccine has been tried in African children with varying success, but only insecticide-treated bed nets have reduced the mortality. Developments in ancillary treatment may reduce the morbidity and mortality of severe falciparum malaria.


Journal article


Curr Opin Pediatr

Publication Date





16 - 20


Animals, Child, Exchange Transfusion, Whole Blood, Humans, Malaria Vaccines, Malaria, Falciparum, Plasmodium falciparum, Prognosis