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Leaves of higher plants develop in a sequential manner from the shoot apical meristem. Previously it was determined that perturbed leaf development in maize rough sheath2 (rs2) mutant plants results from ectopic expression of knotted1-like (knox) homeobox genes. Here, the rs2 gene sequence was found to be similar to the Antirrhinum PHANTASTICA (PHAN) gene sequence, which encodes a Myb-like transcription factor. RS2 and PHAN are both required to prevent the accumulation of knox gene products in maize and Antirrhinum leaves, respectively. However, rs2 and phan mutant phenotypes differ, highlighting fundamental differences in monocot and dicot leaf development programs.

Original publication

DOI

10.1126/science.284.5411.154

Type

Journal article

Journal

Science

Publication Date

02/04/1999

Volume

284

Pages

154 - 156

Keywords

Amino Acid Sequence, Cloning, Molecular, DNA-Binding Proteins, Down-Regulation, Gene Expression Regulation, Plant, Genes, Homeobox, Genes, Plant, Homeodomain Proteins, In Situ Hybridization, Molecular Sequence Data, Mutation, Phenotype, Plant Development, Plant Leaves, Plant Proteins, Plants, Proto-Oncogene Proteins c-myb, Repressor Proteins, Sequence Alignment, Zea mays