Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

We present neuropsychological and transcranial magnetic stimulation (TMS) evidence with normal readers, that the effects of case mixing and contrast reduction on word identification are qualitatively different. Lesions and TMS applied to the right parietal lobe selectively disrupted the identification of mixed relative to single-case stimuli. Bilateral lesions and TMS applied to the occipital cortex selectively disrupted the identification of low-contrast words. These data suggest that different visual distortions (case mixing, contrast reduction) exert different effects on reading, modulated by contrasting brain regions. Case mixing is a "special" distortion and involves the recruitment of processes that are functionally distinct, and dependent on different regions in the brain, from those required to deal with contrast reduction.

Original publication




Journal article


J Cogn Neurosci

Publication Date





1666 - 1675


Adolescent, Adult, Aged, Functional Laterality, Humans, Language, Magnetic Resonance Imaging, Male, Neuropsychological Tests, Occipital Lobe, Parietal Lobe, Psycholinguistics, Psychomotor Performance, Reaction Time, Reading, Recognition, Psychology, Stroke, Transcranial Magnetic Stimulation, Visual Fields