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There is increasing evidence that different transcription units are transcribed together in discrete nuclear structures known as transcription factories. Various new techniques enable us to detect and characterize these structures. We review the latest findings and discuss how they support a model for transcription and chromosome organization.

Original publication

DOI

10.1042/BST0360585

Type

Journal article

Journal

Biochem Soc Trans

Publication Date

08/2008

Volume

36

Pages

585 - 589

Keywords

Animals, Cell Nucleus, Genome, Humans, Models, Genetic, Transcription, Genetic