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Chemokine-chemokine receptor interactions mediate constitutive leukocyte trafficking and leukocyte recruitment to sites of infection and inflammation. We suggest that a multiplicity of leukocyte chemoattractants exists to increase the selectivity of leukocyte recruitment in a range of physiological and pathological settings.


Journal article


Microbes Infect

Publication Date





331 - 336


Acute Disease, Arteriosclerosis, Cell Movement, Chemokines, Communicable Diseases, Humans, Hypersensitivity, Inflammation, Leukocytes, Macrophages, Receptors, Chemokine, Signal Transduction