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Recent evidence suggests that active RNA polymerases are concentrated in discrete 'factories' where they work together on many different templates. The evidence that such factories specialize in the transcription of particular groups of genes is reviewed.

Type

Journal article

Journal

Crit Rev Eukaryot Gene Expr

Publication Date

2000

Volume

10

Pages

21 - 29

Keywords

Cell Nucleolus, Cell Nucleus, DNA-Directed RNA Polymerases, HeLa Cells, Humans, Transcription Factors, Transcription, Genetic