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We have investigated the effects of agents interfering with the cAMP pathway on the rate of miniature IPSCs in cerebellar slices. Noradrenaline and group II glutamate metabotropic receptor agonists respectively enhance and reduce the rate of miniature IPSCs, presumably because they respectively increase and decrease the presynaptic concentration of cAMP.


Journal article


J Physiol Paris

Publication Date





327 - 328


Adenine, Adenylyl Cyclase Inhibitors, Animals, Cerebellum, Cyclic AMP, Cyclic AMP-Dependent Protein Kinases, Enzyme Inhibitors, In Vitro Techniques, Membrane Potentials, Rats, Receptors, Metabotropic Glutamate, Staurosporine, Synapses, Thionucleotides, gamma-Aminobutyric Acid