FORMIC ACID
ANTHONY D.
This dataset contains raw LC–MS data generated during the evaluation of formic acid (FA) pre-treatment for serum and plasma sample preparation in untargeted metabolomics. Samples were extracted using acetonitrile (MeCN) with and without 1% (v/v) FA pre-treatment, and a control set was prepared by post-spiking FA into extracts after MeCN precipitation. Analyses were performed using reversed-phase LC–MS (RPLC–MS) in both positive and negative electrospray ionisation modes, as well as anion-exchange chromatography MS (AEC–MS) in negative mode. The dataset includes all raw files from these test extractions, enabling comparison of metabolite feature detection and signal profiles across the three extraction conditions.