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Linear regression analysis was used to compare penicillin MICs determined with 3,129 recent clinical isolates of Streptococcus pneumoniae to MICs obtained with nine other beta-lactam antimicrobial agents. A strong correlation between penicillin MICs and those obtained with other beta-lactams was demonstrated. It may be possible to test penicillin and use MICs obtained with penicillin to predict MICs of other beta-lactam antimicrobials for Streptococcus pneumoniae.

Original publication

DOI

10.1128/JCM.39.1.367-369.2001

Type

Journal article

Journal

J Clin Microbiol

Publication Date

01/2001

Volume

39

Pages

367 - 369

Keywords

Anti-Bacterial Agents, Humans, Linear Models, Microbial Sensitivity Tests, Penicillins, Pneumococcal Infections, Predictive Value of Tests, Streptococcus pneumoniae, beta-Lactams