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The duplication-degeneration-complementation model of duplicate gene preservation by subfunctionalisation is currently the best explanation for the high level of retention of duplicate genes in early vertebrate evolution. But a direct test of the applicability of this model to such ancient evolutionary events may be difficult. More likely, recent duplications in other lineages will allow us to establish general principles concerning the fate of genes of different types that are duplicated in different ways. These principles may be then extrapolated to understanding the early evolution of the vertebrates.

Type

Journal article

Journal

Curr Opin Genet Dev

Publication Date

08/2002

Volume

12

Pages

393 - 396

Keywords

Animals, Evolution, Molecular, Gene Duplication, Vertebrates