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Comparison of whole genome sequences of representative animals enables reconstruction of the ancestral bilaterian genome: the starting point from which most extant animal lineages evolved. The Hox gene cluster patterns the anterior-posterior axis of bilaterians. Here we show that this cluster was embedded within a larger homeobox gene cluster, the Super-Hox cluster, in the ancestral bilaterian. This Super-Hox cluster contained at least eight genes alongside the core Hox genes ('EuHox' genes).

Original publication

DOI

10.1016/j.tig.2007.09.006

Type

Journal article

Journal

Trends Genet

Publication Date

06/2008

Volume

24

Pages

259 - 262

Keywords

Animals, Beetles, Evolution, Molecular, Genes, Homeobox, Genes, Insect, Genome, Multigene Family